one cut domain family member 3 (transcription factor ONECUT-3, OC-3, ONECUT3)

Function

• transcriptional activator
• binds consensus DNA sequence 5'-DHWATTGAYTWWD-3' on gene promoters, including HNF3B & TTR genes

Structure

• contains 1 CUT DNA-binding domain
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

More general terms

• homeobox protein
• transcription factor (TF)

Database

• UniProt: http://www.uniprot.org/uniprot/O60422.html