TATA box-binding protein-like protein 2 (TBP-like protein 2, TATA box-binding protein-related factor 3, TBP-related factor 3, TBPL2, TRF3)

Function

• transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes
• the complex replaces TFIID at specific promoters at an early stage in the differentiation process (putative)
• interacts with TAF3 (putative)

Structure

belongs to the TBP family

Compartment

• cytoplasm. nucleus
• present in the cytoplasm during cytokenesis

Expression

• ubiquitously expressed in all tissues examined
• highest levels in heart, lung, ovary, spleen & testes

More general terms

• transcription factor (TF)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3873
• UniProt: http://www.uniprot.org/uniprot/Q6SJ96.html