ELL-associated factor 1 (EAF1)

Function

• transcriptional transactivator of ELL & ELL2 elongation activities
• interacts with ELL & ELL2

Structure

• belongs to the EAF family

Compartment

• nucleus, nuclear speckle, Cajal body
• colocalizes with ELL to nuclear speckles

Expression

• expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine & colon > thymus

More general terms

• transcription factor (TF)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/608315
• UniProt: http://www.uniprot.org/uniprot/Q96JC9.html