RNA polymerase II elongation factor ELL2 (ELL2)

Function

• transcription elongation factor
• can increase the catalytic rate of RNA polymerase 2 transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA
• interacts with EAF1 & EAF2

Structure

belongs to the ELL/occludin family

Compartment

nucleus

More general terms

• nuclear protein
• phosphoprotein
• human longevity protein

Additional terms

• RNA polymerase-2

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=22936
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:22936
• OMIM: https://mirror.omim.org/entry/601874
• UniProt: http://www.uniprot.org/uniprot/O00472.html