thyroid transcription factor 1-associated protein 26 (TTF-1-associated protein 26, TTF-1-associated protein BR2, coiled-coil domain-containing protein 59, CCDC59, BR22, TAP26, HSPC128)

Function

• component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) & -C (SFTPC)
• enhance thyroid transcription factor 1 (TITF1)-activated SFTPB & SFTPC promoter activities
• interacts with TITF1

Structure

belongs to the TAP26 family

Compartment

nucleus (probable)

Expression

• ubiquitously expressed
• in lung, expression restricted to alveolar epithelial cells

More general terms

• transcription factor (TF)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9P031.html