POU domain, class 2, transcription factor 3 (octamer-binding transcription factor 11, Oct-11, transcription factor Skn-1, PLA-1 protein, POU2F3, OTF11, PLA1)

Function

• transcription factor binds to the octamer motif (5'-ATTTGCAT-3')
• regulates expression of genes, including SPRR2A or placental lactogen

Structure

• belongs to the POU transcription factor family, class-2 subfamily
• contains 1 homeobox DNA-binding domain
• contains 1 POU-specific domain

Compartment

nucleus

Expression

• specifically expressed in epidermis & cultured keratinocytes

More general terms

• transcription factor (TF)

Database

• OMIM: https://mirror.omim.org/entry/607394
• UniProt: http://www.uniprot.org/uniprot/Q9UKI9.html