chorionic somatomammotropin hormone; choriomammotropin; lactogen; placental lactogen; PL

Function

• produced only during pregnancy
• involved in stimulating lactation, fetal growth & metabolism
• does not interact with GHR
• activates PRLR through Zn+2-induced dimerization

Structure

• belongs to the somatotropin/prolactin family
• CSH1 sequence only differs from CSH2 sequence in 1 amino acid residue

Compartment

secreted

Notes

• apparently 2 different choriomammotropins that differ by only
  • amino acid residue

More general terms

• secreted peptide
• gonadotropin

More specific terms

• chorionic somatomammotropin hormone 1; choriomammotropin-1 (CSH1)
• chorionic somatomammotropin hormone 2; choriomammotropin-2 (CSH2)
• chorionic somatomammotropin hormone-like 1; chorionic somatomammotropin-like; lactogen-like (CSHL1, CSHP1, CSL)