erythroid differentiation related factor; erythroid associated factor; ERAF; alpha-hemoglobin-stabilizing protein; AHSP (EDRF)

Function

• chaperone to prevent aggregation of alpha-globin during erythroid cell maturation
• protects free alpha-globin from precipitation

Pathology

• modulates pathological states of alpha-globin excess, i.e. beta-thalassemia

More general terms

• transcription factor (TF)

Database

• OMIM: https://mirror.omim.org/entry/605821
• UniProt: http://www.uniprot.org/uniprot/Q9NZD4.html