G-protein coupled receptor; serpentine receptor
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Introduction
- the human genome encodes ~350 G protein-coupled receptors
- ~ 1/2 of these have unknown functions
Function
- G-protein coupled receptor detect hormones, growth factors & other endogenous ligands
- as the name implies, they are coupled to G proteins which act as second messengers
Structure
- 7 transmembrane domains
- N-terminal exoplasmic domain; C-terminal cytoplasmic domainS
- cationic, amphophilic sequences on the cytoplasmic faces of receptors are required for G protein regulation
- C-terminal Cys may serve as palmitoylation site
Comparative biology
- G protein-coupled receptors are found only in eukaryotes
More general terms
More specific terms
- 2-oxoglutarate receptor 1; alpha-ketoglutarate receptor 1; G-protein coupled receptor 80; G-protein coupled receptor 99; P2Y purinoceptor 15; P2Y-like nucleotide receptor; P2Y-like GPCR (OXGR1, GPR80, GPR99, P2RY15, P2Y15)
- adenosine diphosphate [ADP] receptor
- adenosine receptor
- adhesion G protein-coupled receptor G1; G-protein coupled receptor 56; protein TM7XN1 (GPR56, TM7LN4, TM7XN1, AGRG1, ADGRG1, UNQ540/PRO1083)
- adrenergic receptor
- angiotensin-2 receptor
- apelin receptor; APJ receptor; G-protein coupled receptor APJ; angiotensin receptor-like 1; HG11 (APLNR, AGTRL1, APJ)
- atypical chemokine receptor; chemokine-scavenging receptor; chemokine decoy receptor
- bombesin receptor
- bradykinin receptor
- brain-specific angiogenesis inhibitor
- G protein-coupled receptor 9; C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; interferon-inducible protein 10 receptor; IP-10 receptor; CKR-L2; CD183 (CXCR3, GPR9)
- C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1; monocyte-derived receptor 15; MDR-15; CD185 (CXCR5, BLR1, MDR15)
- C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; CDw186; CD186 (CXCR6, BONZO, STRL33, TYMSTR)
- C3a anaphylatoxin chemotactic receptor; C3a-R; C3AR (C3AR1 AZ3B C3R1 HNFAG09)
- C5a anaphylatoxin chemotactic receptor 2; complement component 5a receptor 2; G-protein coupled receptor 77 (C5AR2, C5L2, GPR77)
- calcitonin gene-related peptide [CGRP] receptor (CALCRL, CGRPR)
- calcitonin receptor; CT-R (CALCR)
- cannabinoid receptor
- CC chemokine receptor
- CD88; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR (C5AR1, C5AR, C5R1)
- CD97 antigen; Leukocyte antigen CD97; CD97; contains CD97 antigen subunit alpha & CD97 antigen subunit beta (CD97)
- G protein coupled receptor GPR5, C chemokine receptor 1 or XC chemokine receptor 1
- cholecystokinin receptor type A; CCK-A receptor; CCK-AR; cholecystokinin-1 receptor; CCK1-R (CCKAR, CCKRA)
- corticotropin-releasing factor/hormone [CRF/CRH] receptor
- CX3C chemokine receptor 1; C-X3-C CKR-1; CX3CR1; fractalkine receptor; G-protein coupled receptor 13; V28; beta chemokine receptor-like 1; CMK-BRL-1; CMKBLR1 (CX3CR1, CMKBRL1, GPR13)
- cysteinyl leukotriene receptor 1 (CysLTR1, cysteinyl leukotriene D4 receptor, LTD4 receptor, HG55, HMTMF81)
- cysteinyl leukotriene receptor 2 (CysLTR2, PSEC0146, HG57, HPN321, hGPCR21)
- Duffy antigen/chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; plasmodium vivax receptor; CD234 (DARC, FY, GPD)
- EGF, latrophilin & seven transmembrane domain-containing protein 1 (EGF-TM7-latrophilin-related protein, ETL protein, ELTD1, ETL, UNQ202/PRO228)
- EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module EMR2; CD312 antigen (CD312, EMR2)
- endorphin receptor or opioid receptor
- endothelin B receptor-like protein 2 (ETBR-LP-2, G-protein coupled receptor 37-like 1, GPR37L1, ETBRLP2)
- endothelin receptor
- extracellular Ca+2-sensing receptor; CaSR; parathyroid cell Ca+2-sensing receptor; PCaR1 (CASR, GPRC2A, PCAR1)
- fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor (FPR1)
- follicle-stimulating hormone receptor; FSH-R; follitropin receptor (FSHR, LGR1)
- G-protein coupled receptor 40; free fatty acid receptor 1 (FFAR1, GPR40)
- G-protein coupled receptor 43; free fatty acid receptor 2 (FFAR2, GPR43)
- G-protein coupled receptor 41; free fatty acid receptor 3 (FFAR3 GPR41)
- G protein-coupled receptor 101 (GPR101)
- G protein-coupled receptor 103; orexigenic neuropeptide QRFP receptor; pyroglutamylated RFamide peptide receptor (SP9155, AQ27, QRFPR, GPR103)
- G protein-coupled receptor 123 (GPR123, KIAA1828)
- G protein-coupled receptor 127; EGF-like module containing mucin-like hormone receptor-like 4 (GPR127, EMR4, EMR4P)
- G protein-coupled receptor 128 (GPR128)
- G protein-coupled receptor 143 (ocular albinism type 1 protein, GPR143, OA1)
- G protein-coupled receptor 150 (GPR150)
- G protein-coupled receptor 151 (G protein-coupled receptor PGR7, GPCR-2037, GPR151)
- G protein-coupled receptor 152 (G protein-coupled receptor PGR5)
- G protein-coupled receptor 160 (GPR160, GPCR150)
- G protein-coupled receptor 161 (G-protein coupled receptor RE2, GPR161)
- G protein-coupled receptor 24; melanin-concentrating hormone receptor 1; MCH receptor 1; MCHR-1; MCH-R1; MCH1R; MCH-1R; MCHR; somatostatin receptor-like protein; SLC-1 (GPR24, SLC1, MCHR1)
- G protein-coupled receptor 26 (GPR26)
- G protein-coupled receptor 78 (GPR78, UNQ5925/PRO19818)
- G protein-coupled receptor 82 (GPR82)
- G protein-coupled receptor family C group 5 member D (GPRC5D)
- G protein-coupled receptor for asthma susceptibility (G-protein coupled receptor 154, vasopression-related receptor 1, neuropeptide S receptor, G-protein coupled receptor PGR14, NPSR1, GPR154, VPR1, GPRA, PGR14)
- G protein-coupled receptor GPR14 (urotensin II receptor, UR-II-R, UTS2R, GPR14)
- G protein-coupled receptor GPR44; prostaglandin D2 receptor DP2; chemoattractant receptor-homologous molecule expressed on Th2 cells (PTGDR2, CRTH2, DP2)
- G protein-coupled receptor GPR45 (GPR45, PSP24-alpha, PSP24-1)
- G protein-coupled receptor GPR62 (hGPCR8)
- G protein-coupled receptor GPR81; FKSG80 protein (GPR81, HCAR1, FKSG80)
- G protein-coupled receptor GPR85 (super conserved receptor expressed in brain 2, PKrCx1)
- G-protein coupled bile acid receptor 1 (membrane-type receptor for bile acids, M-BAR, hGPCR19, BG37, hBG37, GPBAR1, TGR5)
- G-protein coupled estrogen receptor 1; chemoattractant receptor-like 2; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; G protein-coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-Br; IL8-related receptor DRY12; lymphocyte-...
- G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; niacin receptor 2; nicotinic acid receptor 2 (GPR109B, HM74B, NIACR2, HCAR3)
- G-protein coupled receptor 110 (G-protein coupled receptor PGR19, G-protein coupled receptor KPG-012, GPR110, PGR19)
- G-protein coupled receptor 111 (G-protein coupled receptor PGR20, GPR111, PGR20)
- G-protein coupled receptor 112 (GPR112)
- G-protein coupled receptor 113 (G-protein coupled receptor PGR23, GPR113, PGR23, UNQ9196/PRO34000)
- G-protein coupled receptor 114; GPR114; G-protein coupled receptor PGR27 (PGR27, UNQ2524/PRO6017)
- G-protein coupled receptor 115 (G-protein coupled receptor PGR18, GPR115, PGR18)
- G-protein coupled receptor 116 (GPR116, KIAA0758)
- G-protein coupled receptor 119 (GPR119)
- G-protein coupled receptor 120; free fatty acid receptor 4; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; omega-3 fatty acid receptor 1 (FFAR4, GPR120, GPR129, O3FAR1, PGR4)
- G-protein coupled receptor 125 (GPR125)
- G-protein coupled receptor 126 (GPR126)
- G-protein coupled receptor 132 (G2 accumulation protein, GPR132, G2A)
- G-protein coupled receptor 133 (G-protein coupled receptor PGR25, GPR133, PGR25)
- G-protein coupled receptor 135 (GPR135)
- G-protein coupled receptor 139 (GPR139, Gq-coupled orphan receptor GPRg1, G-protein-coupled receptor PGR3, GPRG1, PGR3)
- G-protein coupled receptor 141 (G-protein coupled receptor PGR13, GPR141, PGR13)
- G-protein coupled receptor 142 (G-protein coupled receptor PGR2, GPR142, PGR2)
- G-protein coupled receptor 144 (G-protein coupled receptor PGR24, GPR144, PGR24)
- G-protein coupled receptor 146 (G-protein coupled receptor PGR8, GPR146, PGR8)
- G-protein coupled receptor 148 (G-protein coupled receptor PGR6, brain & testis restricted GPCR, GPR148, BTR, PGR6)
- G-protein coupled receptor 149 (G-protein coupled receptor PGR10, GPR149, PGR10)
- G-protein coupled receptor 153 (G-protein coupled receptor PGR1, GPR153, PGR1)
- G-protein coupled receptor 155 (G-protein coupled receptor PGR22, GPR155, PGR22)
- G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor, G-protein coupled receptor PGR28, GPR156, GABABL, PGR28)
- G-protein coupled receptor 157 (GPR157)
- G-protein coupled receptor 158 (GPR158, KIAA1136)
- G-protein coupled receptor 15; BOB (GPR15)
- G-protein coupled receptor 162 (gene-rich cluster gene A protein, GPR162, GRCA)
- G-protein coupled receptor 171; G-protein coupled receptor H963 (GPR171, H963)
- G-protein coupled receptor 176 (GPR176, HB-954)
- G-protein coupled receptor 179 (G-protein coupled receptor 158-like 1, GPR179, GPR158L1)
- G-protein coupled receptor 17; uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; P2Y-like receptor; R12 (GPR17)
- G-protein coupled receptor 182; adrenomedullin receptor (GPR182, ADMR)
- G-protein coupled receptor 183; EBV-induced G-protein coupled receptor 2 (GPR183, EBI2)
- G-protein coupled receptor 18; N-arachidonyl glycine receptor; NAGly receptor (GPR18, GPCRW)
- G-protein coupled receptor 19; GPR-NGA (GPR19)
- G-protein coupled receptor 20 (GPR20)
- G-protein coupled receptor 21 (GPR21)
- G-protein coupled receptor 22 (GPR22)
- G-protein coupled receptor 25 (GPR25)
- G-protein coupled receptor 27; super conserved receptor expressed in brain 1 (GPR27, SREB1)
- G-protein coupled receptor 31 (GPR31)
- G-protein coupled receptor 32 (GPR32)
- G-protein coupled receptor 33 (GPR33)
- G-protein coupled receptor 34 (GPR34)
- G-protein coupled receptor 35; kynurenic acid receptor; KYNA receptor (GPR35)
- G-protein coupled receptor 37; endothelin B receptor-like protein 1; ETBR-LP-1; parkin-associated endothelin receptor-like receptor; PAELR (GPR37)
- G-protein coupled receptor 38; motilin receptor (MLNR, GPR38, MTLR, MTLR1)
- G-protein coupled receptor 39 (GPR39)
- G-protein coupled receptor 42 (GPR42, GPR42P)
- G-protein coupled receptor 52 (GPR52)
- G-protein coupled receptor 55 (GPR55)
- G-protein coupled receptor 61; biogenic amine receptor-like G-protein coupled receptor (GPR61, BALGR)
- G-protein coupled receptor 63; PSP24-2; PSP24-beta (GPR63, PSP24B)
- G-protein coupled receptor 64; human epididymis-specific protein 6; He6 (GPR64, HE6, TM7LN2)
- G-protein coupled receptor 75 (GPR75)
- G-protein coupled receptor 83; G-protein coupled receptor 72 (GPR83, GPR72, KIAA1540)
- G-protein coupled receptor 84 (inflammation-related G-protein coupled receptor EX33, GPR84, EX33)
- G-protein coupled receptor 87; G-protein coupled receptor 95 (GPR87, GPR95, FKSG78)
- G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor, GPR88, STRG)
- G-protein coupled receptor family C group 5 member B; A-69G12.1; retinoic acid-induced gene 2 protein; RAIG-2 (GPRC5B, RAIG2)
- G-protein coupled receptor family C group 5 member C; retinoic acid-induced gene 3 protein; RAIG-3 (GPRC5C RAIG3 PSEC0087)
- G-protein coupled receptor family C group 6 member A (hGPRC6A, G-protein coupled receptor 33, hGPCR33, GPRC6A GPCR33)
- G-protein coupled receptor GPCR39; hGPRC39 (GPCR39)
- G-protein coupled receptor PGR26 (G-protein coupled receptor 97, GPR97, PGR26)
- galanin receptor
- gamma-aminobutyric acid (GABA) B receptor
- gastric inhibitory polypeptide receptor; GIP receptor; GIP-R; glucose-dependent insulinotropic polypeptide receptor (GIPR)
- gastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor (GRPR)
- gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; cholecystokinin-2 receptor; CCK2-R (CCKBR, CCKRB)
- glucagon receptor; GL-R (GCGR)
- glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R (GLP1R)
- glucagon-like peptide 2 receptor; GLP-2 receptor; GLP-2-R; GLP-2R (GLP2R)
- gonadotropin-releasing hormone 2 [GNRH2] receptor
- gonadotropin-releasing hormone [GNRH] receptor
- growth hormone secretagogue receptor type 1; GHS-R; GH-releasing peptide receptor; GHRP; ghrelin receptor (GHSR)
- growth hormone-releasing hormone receptor; GHRH receptor; GRF receptor; GRFR (GHRHR)
- histamine receptor
- hypocretin receptor; orexin receptor (Hcrtr)
- KiSS-1 receptor (KiSS-1R, kisspeptins receptor, metastin receptor, G-protein coupled receptor 54, hypogonadotropin-1, hOT7T175, KISS1R, AXOR12, GPR54, OT7T175)
- latrophilin (Ca+2-independent alpha-latrotoxin receptor, lectomedin)
- leucine-rich repeat G protein-coupled receptor 6
- leucine-rich repeat G protein-coupled receptor 7
- leucine-rich repeat G protein-coupled receptor 8
- leucine-rich repeat-containing G protein-coupled receptor
- leukotriene B4 receptor 2 (LTB4-R2, 7 transmembrane receptor BLTR2, leukotriene B4 receptor BLT2, LTB4 receptor JULF2)
- Lutropin-choriogonadotropic hormone receptor; LH/CG-R; LSH-R; Luteinizing hormone receptor; LHR (LHCGR, LCGR, LGR2 LHRHR)
- lysophosphatidic acid receptor (LPA-R)
- lysophosphatidic acid receptor 5; LPA receptor 5; LPA-5; G-protein coupled receptor 92; G-protein coupled receptor 93 (LPAR5, GPR92, GPR93)
- mas-related G protein coupled receptor
- melanin-concentrating hormone receptor 2 (MCH receptor 2, MCHR-2, MCH-R2, MCH2R, MCH-2R, MCH2, G protein coupled receptor 145, GPRv17, GPR145, MCHR2, SLT)
- melanocortin receptor
- melatonin receptor
- G protein-coupled receptor 50; melatonin-related receptor; H9 (GPR50)
- metabotropic glutamate receptor
- muscarinic receptor
- N-formyl peptide receptor 2; FMLP-related receptor I; FMLP-R-I; formyl peptide receptor-like 1; lipoxin A4 receptor; LXA4 receptor; RFP; HM63 (FPR2 FPRH1 FPRL1 LXA4R)
- N-formyl peptide receptor 3; FMLP-related receptor II; FMLP-R-II; formyl peptide receptor-like 2 (FPR3, FPRH1, FPRL2)
- neuromedin U receptor 2 (G-protein coupled receptor TGR-1, G-protein coupled receptor FM-4, NMUR2, TGR1)
- neuromedin-B receptor; NMB-R; neuromedin-B-preferring bombesin receptor (NMBR)
- neuromedin-K receptor; NKR; neurokinin B receptor; NK-3 receptor; NK-3R; tachykinin receptor 3 (TACR3, NK3R, TAC3R)
- neuromedin-U receptor 1; NMU-R1; G-protein coupled receptor 66; G-protein coupled receptor FM-3 (NMUR1, GPR66)
- neuropeptide FF receptor 1; G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022 (NPFFR1, GPR147, NPFF1)
- neuropeptide FF receptor 2; G-protein coupled receptor 74; G-protein coupled receptor HLWAR77; neuropeptide G-protein coupled receptor (NPFFR2, GPR74, NPFF2, NPGPR)
- neuropeptide Y receptor
- neuropeptides B/W receptor type 1; G-protein coupled receptor 7 (NPBWR1, GPR7)
- neuropeptides B/W receptor type 2; G-protein coupled receptor 8 (NPBWR2, GPR8)
- neurotensin receptor type 1; NT-R-1; high-affinity levocabastine-insensitive neurotensin receptor; NTRH (NTSR1 NTRR)
- neurotensin receptor type 2; NTR2 receptor; NT-R-2; Levocabastine-sensitive neurotensin receptor (NTSR2)
- nicotinic acid receptor 1; G-protein coupled receptor 109A; G-protein coupled receptor HM74A (GPR109A, HCAR2, HM74A)
- odorant receptor
- olfactory receptor
- opsin
- ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A; sphingosylphosphorylcholine receptor (GPR68 OGR1)
- oxoeicosanoid receptor 1 (G-protein coupled receptor TG1019, 5-oxo-ETE G-protein coupled receptor, G-protein coupled receptor 170, G-protein coupled receptor R527, OXER1, GPR170, TG1019)
- oxytocin receptor; OT-R (OXTR)
- G-protein coupled receptor 86; P2Y purinoceptor 13; P2Y13; G-protein coupled receptor 94 (P2RY13, GPR86, GPR94, FKSG77)
- P2Y purinoceptor 14; P2Y14; G-protein coupled receptor 105; UDP-glucose receptor (P2RY14, GPR105, KIAA0001)
- P2Y purinoceptor 8 (P2Y8, P2RY8)
- P2Y purinoceptor or P2Y purinergic receptor
- parathyroid hormone 2 receptor; PTH2 receptor (PTH2R PTHR2)
- parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor (PTHR1, PTHR, PTH1R)
- pituitary adenyl cyclase activating polypeptide [PACAP] receptor
- platelet-activating factor receptor; PAF-R (PTAFR PAFR)
- probable G-protein coupled receptor 1 (GPR1)
- probable G-protein coupled receptor 12 (GPR12)
- probable G-protein coupled receptor 173; super conserved receptor expressed in brain 3 (GPR173, SREB3)
- probable G-protein coupled receptor 3; ACCA orphan receptor (GPR3, ACCA)
- probable G-protein coupled receptor 4; G-protein coupled receptor 19 (GPR4 GPR19)
- prokineticin receptor 1 (PK-R1, G protein-coupled receptor 73, GPR73a, G protein-coupled receptor ZAQ, GPR73, PKR1, PROKR1)
- prokineticin receptor 2; PK-R2; G protein-coupled receptor 73-like 1 (PROKR2, GPR73b, GPRg2, GPR73L1, PKR2)
- prolactin-releasing peptide receptor; PrRP receptor; PrRPR; G-protein coupled receptor 10; hGR3 (PRLHR, GPR10, GR3)
- prostacyclin receptor; prostanoid IP receptor; PGI receptor; prostaglandin I2 receptor (PTGIR, PRIPR)
- prostaglandin D2 receptor DP1 (Prostanoid DP receptor, PGD receptor)
- prostaglandin F2-alpha receptor; PGF2 alpha receptor; prostanoid FP receptor; PGF receptor (PTGFR)
- prostaglandin-E [PGE] receptor
- proteinase-activated receptor 2; PAR-2; thrombin receptor-like 1; coagulation factor II receptor-like 1; G-protein coupled receptor 11 (F2RL1, GPR11, PAR2)
- proteinase-activated receptor 3; PAR-3; thrombin receptor-like 2; coagulation factor II receptor-like 2 (F2RL2, PAR3)
- proteinase-activated receptor 4; PAR-4; thrombin receptor-like 3; coagulation factor II receptor-like 3 (F2RL3, PAR4)
- G protein-coupled receptor 65 (GPR65, psychosine receptor, T cell-death associated protein 8, TDAG8)
- relaxin-3 receptor 1 (RLN3 receptor 1, relaxin family peptide receptor 3, somatostatin- and angiotensin-like peptide receptor, G protein-coupled receptor SALPR, GPCR135, RXFP3, RLN3R1, SALPR)
- relaxin-3 receptor 2; relaxin family peptide receptor 4; G-protein coupled receptor 100; GPCR142 (RXFP4, GPR100, RLN3R2)
- retinoic acid induced 3 protein (G protein-coupled receptor family C group 5 member A, retinoic acid induced gene 1 protein, RAIG-1, orphan G protein-coupling receptor PEIG-1, RAI3, GPRC5A, RAIG1)
- Rhodopsin; opsin-2 (RHO OPN2)
- RPE-retinal G protein-coupled receptor (RGR)
- secretin receptor; SCT-R (SCTR)
- serotonin [5HT]-1 receptor
- serotonin [5HT]-2 receptor
- serotonin [5HT]-4 receptor; 5-hydroxytryptamine receptor 4; 5-HT-4; 5-HT4; serotonin receptor 4 (HTR4)
- serotonin [5HT]-5 receptor
- serotonin [5HT]-6 receptor; 5-hydroxytryptamine receptor 6; 5-HT-6; serotonin receptor 6 (HTR6)
- serotonin [5HT]-7 receptor; 5-hydroxytryptamine receptor 7; 5-HT-7; 5HT7; 5-HT-X; serotonin receptor 7 (HTR7)
- smoothened homolog; SMO; Gx protein (SMO, SMOH)
- somatostatin receptor
- sphingosine 1-phosphate receptor GPR6; G-protein coupled receptor 6 (GPR6)
- sphingosine 1-phosphate receptor; S1P receptor (S1PR)
- substance-K receptor; SKR; neurokinin A receptor; NK-2 receptor; NK-2R; tachykinin receptor 2 (TACR2, NK2R, NKNAR, TAC2R)
- substance-P receptor; SPR; NK-1 receptor; NK-1R; Tachykinin receptor 1 (TACR1, NK1R, TAC1R)
- succinate receptor 1; G-protein coupled receptor 91; P2Y purinoceptor 1-like (SUCNR1, GPR91)
- taste receptor, type 1
- taste receptor, type 2
- thrombin receptor; proteinase-activated receptor 1; PAR-1; coagulation factor 2 receptor (F2R, CF2R, PAR1, TR)
- Thromboxane A2 receptor; TXA2-R; prostanoid TP receptor (TBXA2R)
- thyrotropin receptor; thyroid-stimulating hormone receptor; TSH-R (TSHR LGR3)
- thyrotropin-releasing hormone receptor; TRH-R; thyroliberin receptor (TRHR)
- trace amine receptor 5; TaR-5; G protein-coupled receptor GPR102 (TRAR5, TAAR8)
- trace amine-associated receptor (TAAR)
- G-protein coupled receptor 58; trace amine-associated receptor 2; TaR-2; trace amine receptor 2 (TAAR2, GPR58)
- G-protein coupled receptor 57; trace amine-associated receptor 3; TaR-3; trace amine receptor 3 (TAAR3, GPR57)
- tumor endothelial marker 5; G protein-coupled receptor 124 (GPR124, TEM5, KIAA1531)
- vasoactive intestinal polypeptide [VIP] receptor
- very-large G protein-coupled receptor; monogenic audiogenic seizure susceptibility 1; Usher syndrome type-2C protein; G-protein coupled receptor 98 (VLGR1; MASS1, GPR98, KIAA0686, VLGR1)
- visual pigment-like receptor peropsin (rhodopsin homolog retinal pigment epithelium-derived, RRH, rhodopsin homolog RPE-derived)
- vomeronasal type-1 receptor (V1r-like receptor, VN1R)
References
- ↑ Schofield et al Trends Neurosci 1990 Jan;13(1):8
- ↑ Alberts et al Molecular Biology of the Cell, 2nd ed. 1989, pg 704
- ↑ Higashijima T et al Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity. J Biol Chem 1990 Aug 25;265(24):14176-86 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2117607
- ↑ Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 748
- ↑ Van Tol HH et al Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 350:610 1991 (C-terminal Cys) PMID: https://www.ncbi.nlm.nih.gov/pubmed/2117607
- ↑ Wikipedia: G protein http://en.wikipedia.org/wiki/G_protein
- ↑ Wikipedia: G protein-coupled receptor http://en.wikipedia.org/wiki/G_protein-coupled_receptor