G-protein coupled receptor 18; N-arachidonyl glycine receptor; NAGly receptor (GPR18, GPCRW)

Function

• receptor for N-arachidonyl glycine
• activity mediated by G proteins that inhibit adenylyl cyclase
• may contribute to regulation of the immune system

Structure

• belongs to the G-protein coupled receptor 1 family

Compartment

• cell membrane; multi-pass membrane protein

Expression

• most abundant in testis & spleen
• highly expressed in CD4 & CD8-positive T-cells & CD19-positive B-cells

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2841
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2841
• OMIM: https://mirror.omim.org/entry/602042
• UniProt: http://www.uniprot.org/uniprot/Q14330.html