gonadotropin-releasing hormone 2 [GNRH2] receptor

Function

• mediation of GnRH2 activity
• G-protein coupled to activate a phosphatidylinositol-Ca+2 second messenger system
• phosphorylated on the C-terminal cytoplasmic tail

Structure

belongs to the G-protein coupled receptor 1 family

Alternative splicing

named isoforms=2

Expression

• expressed in many tissues
• questionable expression in humans (evidence suggests it is expressed & functional in humans)

Notes

• stop codon in position 179 & a base insertion just after residue 9 which should NOT allow the correct N-terminal sequence

More general terms

• G-protein coupled receptor; serpentine receptor

Additional terms

• gonadotropin-releasing hormone [GNRH] receptor
• gonadotropin-releasing hormone/factor; gonadoliberin 2; LH/FSH-releasing hormone 2 (GnRH2, LHRH2)

Database

• UniProt: http://www.uniprot.org/uniprot/Q96P88.html