melanin-concentrating hormone receptor 2 (MCH receptor 2, MCHR-2, MCH-R2, MCH2R, MCH-2R, MCH2, G protein coupled receptor 145, GPRv17, GPR145, MCHR2, SLT)

Function

• receptor for melanin-concentrating hormone
• coupled to G proteins that activate phosphoinositide hydrolysis

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• specifically expressed in the brain
• highest levels in cerebral cortex, hippocampus & amygdala
• no expression detected in the cerebellum, thalamus or hypothalamus

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• melanin

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8453
• OMIM: https://mirror.omim.org/entry/606111
• UniProt: http://www.uniprot.org/uniprot/Q969V1.html