neuropeptide FF receptor 1; G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022 (NPFFR1, GPR147, NPFF1)

Function

• receptor for NPAF (A-18-F-amide) & NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides
• can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands
• mediates its action by association with G proteins that activate a phosphatidylinositol-Ca+2 second messenger system

Structure

• belongs to the G-protein coupled receptor 1 family

Compartment

• cell membrane; multi-pass membrane protein

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein
• phosphoprotein

Additional terms

• FMRFamide-related peptides; contains: neuropeptide SF; NPSF; contains: neuropeptide FF; NPFF; contains: neuropeptide AF; NPAF (NPFF)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64106
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:64106
• OMIM: https://mirror.omim.org/entry/607448
• UniProt: http://www.uniprot.org/uniprot/Q9GZQ6.html