G protein-coupled receptor GPR14 (urotensin II receptor, UR-II-R, UTS2R, GPR14)

Function

• high affinity receptor for urotensin-2 & urotensin-2B
• activity is mediated by a G-protein that activates a phosphatidylinositol-Ca+2 second messenger system

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

most abundant expression in the heart & pancreas

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• G-protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2837
• OMIM: https://mirror.omim.org/entry/600896
• UniProt: http://www.uniprot.org/uniprot/Q9UKP6.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2837