G protein-coupled receptor 78 (GPR78, UNQ5925/PRO19818)

Function

orphan receptor

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• expressed in pituitary & placenta
• no expression detected in brain, skeletal muscle, lung, heart, liver, pancreas, or kidney
• expression increased in fibroblasts or HeLa cells following UV-A irradiation, exposure to DNA-alkylating agents, or endoplasmic reticulum (ER) stress caused by osmotic shock or the glycosylation inhibitor tunicamycin

More general terms

• G-protein coupled receptor; serpentine receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2720
• OMIM: https://mirror.omim.org/entry/606921
• UniProt: http://www.uniprot.org/uniprot/Q96P69.html