neuromedin-K receptor; NKR; neurokinin B receptor; NK-3 receptor; NK-3R; tachykinin receptor 3 (TACR3, NK3R, TAC3R)

Function

• receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B)
• rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P
• associated with G proteins that activate a phosphatidylinositol-Ca+2 second messenger system
• anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a Cys

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6870
• OMIM: https://mirror.omim.org/entry/162332
• UniProt: http://www.uniprot.org/uniprot/P29371.html