leukotriene B4 receptor 2 (LTB4-R2, 7 transmembrane receptor BLTR2, leukotriene B4 receptor BLT2, LTB4 receptor JULF2)

Function

• low-affinity receptor for leukotrienes including LTB4
• mediates chemotaxis of granulocytes & macrophages
• G-protein-linked IP3-Ca+2 second messenger system
• rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• widely expressed

Notes

uncertain whether Met-1 or Met-32 is the initiator

More general terms

• G-protein coupled receptor; serpentine receptor
• leukotriene receptor
• glycoprotein

Additional terms

• leukotriene B4

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5641
• OMIM: https://mirror.omim.org/entry/605773
• UniProt: http://www.uniprot.org/uniprot/Q9NPC1.html