prokineticin receptor 1 (PK-R1, G protein-coupled receptor 73, GPR73a, G protein-coupled receptor ZAQ, GPR73, PKR1, PROKR1)

Function

• receptor for prokineticin 1
• exclusively coupled to Gq proteins
• activation leads to mobilization of Ca+2, stimulation of phosphoinositide turnover & activation of p44/p42 mitogen-activated protein kinase

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate & pancreas

More general terms

• G-protein coupled receptor; serpentine receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1088
• OMIM: https://mirror.omim.org/entry/607122
• UniProt: http://www.uniprot.org/uniprot/Q8TCW9.html