substance-P receptor; SPR; NK-1 receptor; NK-1R; Tachykinin receptor 1 (TACR1, NK1R, TAC1R)

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Function

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P25103.html
  2. Wikipedia; Note: Tachykinin entry http://en.wikipedia.org/wiki/Tachykinin
  3. Gerard NP, Eddy RL Jr, Shows TB, Gerard C. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues. J Biol Chem. 1990 Nov 25;265(33):20455-62. Erratum in: J Biol Chem. 1991 Jan 15;266(2):1354. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2173708
  4. Fong TM, Cascieri MA, Yu H, Bansal A, Swain C, Strader CD. Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345. Nature. 1993 Mar 25;362(6418):350-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8384323
  5. Elling CE, Nielsen SM, Schwartz TW. Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor. Nature. 1995 Mar 2;374(6517):74-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7532789

Database