G-protein coupled receptor 116 (GPR116, KIAA0758)

Function

• role in the regulation of acid-base balance (putative)
• proteolytically cleaved, tight association of fragments

Structure

• exists as disulfide-linked dimers at the cell surface
• belongs to the G-protein coupled receptor 2 family, LN-TM7 subfamily
• contains 1 GPS domain
• contains 3 Ig-like domains (immunoglobulin-like)
• contains 1 SEA domain

Compartment

cell membrane

Alternative splicing

named isoforms=2

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IZF2.html