immunoglobulin superfamily domain

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Introduction

Ig constant chain domains & a single extracellular domain of MHC chains are related. These homologous domains are about 100 amino acid residues with a conserved intradomain disulfide.

If intracellular, lacks disulfide bonds

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References

  1. Baron M, Norman DG, Campbell ID. Protein modules. Trends Biochem Sci. 1991 Jan;16(1):13-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2053133
  2. prosite :accession PS00290