glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R (GLP1R)

Function

• receptor for glucagon-like peptide 1
• activity is mediated by G proteins which activate adenylyl cyclase

Structure

belongs to the G-protein coupled receptor 2 family

Compartment

cell membrane

Pharmacology

• incretin mimetics (GLP1R agonists) are use in treatment of diabetes mellitus type 2

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• glucagon-like peptide 1 (GLP-1) receptor agonist; incretin mimetic; GLP-1 mimetic; GLP-1 agonist; glutide; GLP-1RA
• glucagon-like peptide 1 (GLP1)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2740
• OMIM: https://mirror.omim.org/entry/138032
• UniProt: http://www.uniprot.org/uniprot/P43220.html