glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R (GLP1R)
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Function
- receptor for glucagon-like peptide 1
- activity is mediated by G proteins which activate adenylyl cyclase
Structure
belongs to the G-protein coupled receptor 2 family
Compartment
Pharmacology
- incretin mimetics (GLP1R agonists) are use in treatment of diabetes mellitus type 2
More general terms
Additional terms
- glucagon-like peptide 1 (GLP1)
- incretin mimetic; glucagon-like peptide 1 (GLP-1) receptor agonist; GLP-1 mimetic; glutide; GLP-1RA
References
- ↑ UniProt http://www.uniprot.org/uniprot/P43220.html
- ↑ Wikipedia; Note: glucagon-like peptide 1 entry http://en.wikipedia.org/wiki/glucagon-like_peptide-1
- ↑ Holz GG, Habener JF. Signal transduction crosstalk in the endocrine system: pancreatic beta-cells and the glucose competence concept. Trends Biochem Sci. 1992 Oct;17(10):388-93. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1455507