serotonin [5HT]-7 receptor; 5-hydroxytryptamine receptor 7; 5-HT-7; 5HT7; 5-HT-X; serotonin receptor 7 (HTR7)

Function

• one of several receptors for 5-hydroxytryptamine (serotonin)
• activity is mediated by G proteins that stimulate adenylate cyclase (Gs protein)

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Alternative splicing

named isoforms=3

Expression

• isoform A is the predominant isoform in spleen, caudate & hippocampus
• isoform B is expressed at lower levels, & isoform D is a minor isoform

More general terms

• G-protein coupled receptor; serpentine receptor
• serotonin [5HT] receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3363
• OMIM: https://mirror.omim.org/entry/182137
• UniProt: http://www.uniprot.org/uniprot/P34969.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3363