parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor (PTHR1, PTHR, PTH1R)

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Function

Structure

Compartment

cell membrane

Expression

  • expressed in most tissues
  • most abundant in kidney, bone & liver

Pathology

More general terms

More specific terms

Additional terms

References

  1. UniProt http://www.uniprot.org/uniprot/Q03431.html
  2. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=PTHR1
  3. Dunlay R, Hruska K. PTH receptor coupling to phospholipase C is an alternate pathway of signal transduction in bone and kidney. Am J Physiol. 1990 Feb;258(2 Pt 2):F223-31. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2155534
  4. Schipani E et al A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science. 1995 Apr 7;268(5207):98-100. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7701349

Database