prostaglandin F2-alpha receptor; PGF2 alpha receptor; prostanoid FP receptor; PGF receptor (PTGFR)

Function

• receptor for prostaglandin F2-alpha (PGF2-alpha)
• activity is mediated by G proteins which activate a phosphatidylinositol-Ca+2 second messenger system.
• initiates luteolysis in the corpus luteum (putative)

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein
• prostaglandin receptor

Additional terms

• prostaglandin F2-alpha; dinoprost (Lutalyse)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5737
• OMIM: https://mirror.omim.org/entry/600563
• UniProt: http://www.uniprot.org/uniprot/P43088.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5737