gastric inhibitory polypeptide receptor; GIP receptor; GIP-R; glucose-dependent insulinotropic polypeptide receptor (GIPR)

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Function

Structure

belongs to the G-protein coupled receptor 2 family

Compartment

cell membrane

Alternative splicing

named isoforms=2

Expression

Pharmacology

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P48546.html
  2. 2.0 2.1 2.2 2.3 Rosenstock J, Wysham C, Frias JP, et al. Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): A double-blind, randomised, phase 3 trial. Lancet 2021 Jun 25; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34186022 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01324-6/fulltext
    Frias JP, Davies MJ, Rosenstock J et al. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med 2021 Jun 25; [e-pub]. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34170647 https://www.nejm.org/doi/10.1056/NEJMoa2107519
  3. 3.0 3.1 Adriaenssens AE, Biggs EK, Darwish T et al Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake. Cell Metab. 2019 Nov 5;30(5):987-996.e6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31447324 PMCID: PMC6838660 Free PMC article.

Database