EGF, latrophilin & seven transmembrane domain-containing protein 1 (EGF-TM7-latrophilin-related protein, ETL protein, ELTD1, ETL, UNQ202/PRO228)

Function

• cardiac development
• proteolytically cleaved into 2 subunits, a large extracellular region (alpha subunit) non-covalently linked to a seven- transmembrane moiety (beta subunit)

Expression

• mainly expressed in smooth muscle
• up-regulated in the adult heart

More general terms

• G-protein coupled receptor; serpentine receptor

Additional terms

• epidermal growth factor (EGF)/urogastrone
• latrophilin (Ca+2-independent alpha-latrotoxin receptor, lectomedin)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9HBW9.html