substance-K receptor; SKR; neurokinin A receptor; NK-2 receptor; NK-2R; tachykinin receptor 2 (TACR2, NK2R, NKNAR, TAC2R)

Function

• receptor for the tachykinin neuropeptide substance K (neurokinin A)
• associated with G proteins that activate phosphatidylinositol-Ca+2 second messenger system
• affinity to tachykinins is: substance K > neuromedin-K > substance P

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/162321
• UniProt: http://www.uniprot.org/uniprot/P21452.html