gastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor (GRPR)

Function

• receptor for gastrin releasing peptide (GRP)
• mediates its action by association with G proteins that activate a phosphatidylinositol-Ca+2 second messenger system

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• highly expressed in pancreas
• also expressed in stomach, adrenal cortex & brain

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• gastrin-releasing peptide; contains: neuromedin-C; GRP-10 (GRP)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2925
• OMIM: https://mirror.omim.org/entry/305670
• UniProt: http://www.uniprot.org/uniprot/P30550.html