parathyroid hormone 2 receptor; PTH2 receptor (PTH2R PTHR2)

Function

• specific receptor for parathyroid hormone
• activity is mediated by Gs proteins which activate adenylyl cyclase
• may play a significant role in pancreatic function
• PTH2R presence in neurons suggests it may function as a neurotransmitter receptor
• binds to TIPF39/TIP39

Structure

belongs to the G-protein coupled receptor 2 family

Compartment

cell membrane

Expression

• expressed abundantly in brain & pancreas
• also expressed in the testis

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• parathyroid hormone receptors (PTH receptors)
• parathyroid hormone; parathormone; parathyrin (PTH)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5746
• OMIM: https://mirror.omim.org/entry/601469
• UniProt: http://www.uniprot.org/uniprot/P49190.html