relaxin-3 receptor 1 (RLN3 receptor 1, relaxin family peptide receptor 3, somatostatin- and angiotensin-like peptide receptor, G protein-coupled receptor SALPR, GPCR135, RXFP3, RLN3R1, SALPR)

Function

• receptor for relaxin-3
• binding of relaxin-3 inhibits cAMP accumulation

Structure

• belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• expressed predominantly in brain regions
• expressed in substantia nigra & pituitary > hippocampus, spinal cord, amygdala, caudate nucleus, corpus callosum > cerebellum
• in peripheral tissues, expressed in adrenal gland > pancreas, salivary gland, placenta, mammary gland, testis

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• relaxin receptor
• relaxin-3; prorelaxin H3; insulin-like peptide INSL7; insulin-like peptide 7 [Contains: relaxin-3 B chain; relaxin-3 A chain] (RLN3, INSL7, RXN3, ZINS4, UNQ6188/PRO20213)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NSD7.html