relaxin-3; prorelaxin H3; insulin-like peptide INSL7; insulin-like peptide 7 [Contains: relaxin-3 B chain; relaxin-3 A chain] (RLN3, INSL7, RXN3, ZINS4, UNQ6188/PRO20213)

Function

• role in neuropeptide signaling processes
• ligand for LGR7, relaxin-3 receptor-1 (GPCR135) & relaxin-3 receptor-2 (GPCR142)

Structure

• belongs to the insulin family
• heterodimer of a B chain & an A chain linked by 2 disulfide bonds

Compartment

secreted protein

More general terms

• relaxin

Additional terms

• relaxin-3 receptor 2; relaxin family peptide receptor 4; G-protein coupled receptor 100; GPCR142 (RXFP4, GPR100, RLN3R2)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=117579
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:117579
• OMIM: https://mirror.omim.org/entry/606855
• UniProt: http://www.uniprot.org/uniprot/Q8WXF3.html