psychosine receptor (G protein-coupled receptor 65, GPR65, T cell-death associated protein 8, TDAG8)

Function

• receptor for the glycosphingolipid psychosine (PSY) & several related glycosphingolipids
• may play role in activation-induced cell death or in differentiation of T-cells

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta & peripheral blood leukocytes

More general terms

• G-protein coupled receptor; serpentine receptor
• glycoprotein

Additional terms

• psychosine; galactosylsphingosine; sphingosine galactoside

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8477
• OMIM: https://mirror.omim.org/entry/604620
• UniProt: http://www.uniprot.org/uniprot/Q8IYL9.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8477