pruritus (itching)

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Introduction

Itching or pruritus is the unpleasant sensation associated with the urge to scratch.

Classification

Etiology

dermatologic causes (pruritoceptive)

systemic causes (neurogenic)

neurologic (neuropathic)

psychological cause (psychogenic)

Pathology

Clinical manifestations

* images[18]

Laboratory

pruritus without a rash

Radiology

Complications

Management

More general terms

More specific terms

Additional terms

References

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  7. Greaves MW. Recent advances in pathophysiology and current management of itch. Ann Acad Med Singapore. 2007 Sep;36(9):788-92. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17925991
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  9. 9.0 9.1 Zirwas MJ, Seraly MP Pruritus of unknown origin: a retrospective study. J Am Acad Dermatol. 2001 Dec;45(6):892-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11712035
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  11. 11.0 11.1 Fett N, Haynes K, Propert KJ, Margolis DJ. Five-year malignancy incidence in patients with chronic pruritus: a population-based cohort study aimed at limiting unnecessary screening practices. J Am Acad Dermatol. 2014 Apr;70(4):651-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24485529
  12. Cassano N, Tessari G, Vena GA, Girolomoni G Chronic pruritus in the absence of specific skin disease: an update on pathophysiology, diagnosis, and therapy. Am J Clin Dermatol. 2010 Dec 1;11(6):399-411 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20866115
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  14. Stander S, Weisshaar E, Mettang T et al Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol. 2007;87(4):291-4. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17598029
  15. Yosipovitch G, Bernhard JD Clinical practice. Chronic pruritus. N Engl J Med. 2013 Apr 25;368(17):1625-34 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23614588
  16. Patel T, Yosipovitch G. The management of chronic pruritus in the elderly. Skin Therapy Lett. 2010 Sep;15(8):5-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20844849
  17. Butler DF, James WD Medscape: Pruritus and Systemic Disease http://emedicine.medscape.com/article/1098029-overview
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  19. Lambert J. Pruritus in female patients. Biomed Res Int. 2014;2014:541867. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24711996 Free PMC Article
  20. Silverberg JI. Practice Gaps in Pruritus. Dermatol Clin. 2016 Jul;34(3):257-61. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27363881 Free PMC Article
  21. 21.0 21.1 Roh YS, Sutaria N, Biles NF et al Treatment of Chronic Pruritus With Medical Marijuana. JAMA Dermatol. Published online April 9, 2021 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33835147 https://jamanetwork.com/journals/jamadermatology/fullarticle/2778442
  22. 22.0 22.1 Deng J et al. Risk of hematologic cancer in patient with undifferentiated pruritis. JAMA Dermatol 2022 Jul; 158:791. PMID: https://www.ncbi.nlm.nih.gov/pubmed/35612839 PMCID: PMC9134041 (available on 2023-05-25) https://jamanetwork.com/journals/jamadermatology/fullarticle/2792454