calcium channel blocker (CCB)

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Indications

Contraindications

* amlodipine may be OK

Adverse effects

Overdose:

Management of overdose:

Drug interactions

Mechanism of action

More general terms

More specific terms

Additional terms

Component of

References

  1. Jump up to: 1.0 1.1 Joly P et al, Chronic eczematous eruptions of the elderly are associated with chronic exposure to calcium channel blockers: Results from a cases-control study. J Invest Dermatol 2007, 127:2766 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17713574
    Stern RS Chronic medication use and inflammatory skin diseases: The power and limitations of the case-control study. J Invest Dermatol 2007, 127:2709 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18007690
    Prescriber's Letter 15(4): 2008 Calcium Channel Blockers (CCBs) and Eczema Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=240402&pb=PRL (subscription needed) http://www.prescribersletter.com
  2. Jump up to: 2.0 2.1 Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 18. American College of Physicians, Philadelphia 2009, 2012, 2018.
  3. Jump up to: 3.0 3.1 The Washington Manual of Medical Therapeutics, 33rd edition Foster C et al (eds) Lippincott, Williams & Wilkins, Philadelphia, 2010, pg 971
  4. Jump up to: 4.0 4.1 Summers EM et al. Chronic eczematous eruptions in the aging: Further support of an association with exposure to calcium channel blockers. JAMA Dermatol 2013 May 1 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23636109 <Internet> http://archderm.jamanetwork.com/article.aspx?articleid=1684846
  5. Jump up to: 5.0 5.1 Li CI, Daling JR, Tang MT et al Use of Antihypertensive Medications and Breast Cancer Risk Among Women Aged 55 to 74 Years. JAMA Intern Med. August 5, 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23921840 <Internet> http://archinte.jamanetwork.com/article.aspx?articleid=1723871
    Coogan PF Calcium-Channel Blockers and Breast Cancer.A Hypothesis Revived. JAMA Intern Med. August 5, 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23921818 <Internet> http://archinte.jamanetwork.com/article.aspx?articleid=1723870
  6. Jump up to: 6.0 6.1 6.2 Deprecated Reference
  7. Jump up to: 7.0 7.1 InterMountain Health Care. Study deputes previous claims that calcium channel blocker meds cause breast cancer. http://intermountainhealthcare.org/hospitals/imed/services/heart-institute/about/Pages/news.aspx?NewsID=1867
  8. Makani H, Bangalore S, Romero J et al Peripheral edema associated with calcium channel blockers: incidence and withdrawal rate--a meta-analysis of randomized trials. J Hypertens. 2011 Jul;29(7):1270-80. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21558959
  9. Jump up to: 9.0 9.1 Paauw DS Dangerous and Deadly Drug Combinations Medscape. June 30, 2016 http://www.medscape.com/features/slideshow/dangerous-drug-combinations
  10. Jump up to: 10.0 10.1 10.2 10.3 10.4 10.5 10.6 10.7 Lindberg DM Consensus Guidelines for Calcium Channel Blocker Poisoning. NEJM Journal Watch. Oct 14, 2016 Massachusetts Medical Society (subscription needed) http://www.jwatch.org
    St-Onge M, Anseeuw K, Cantrell FL et al. Experts consensus recommendations for the management of calcium channel blocker poisoning in adults. Crit Care Med 2016 Oct 3 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27749343 <Internet> http://journals.lww.com/ccmjournal/pages/articleviewer.aspx?year=9000&issue=00000&article=96757&type=abstract
  11. Jump up to: 11.0 11.1 Savage RD, Visentin JD, Bronskill SE et al. Evaluation of a common prescribing cascade of calcium channel blockers and diuretics in older adults with hypertension. JAMA Intern Med 2020 Feb 24; PMID: https://www.ncbi.nlm.nih.gov/pubmed/32091538 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2761272
  12. Jump up to: 12.0 12.1 NEJM Knowledge+
    DeWitt CR, Waksman JC. Pharmacology, pathophysiology and management of calcium channel blocker and beta-blocker toxicity. Toxicol Rev 2004; 23:223 PMID: https://www.ncbi.nlm.nih.gov/pubmed/15898828
  13. Jump up to: 13.0 13.1 Rochon PA et al. Association of a calcium channel blocker and diuretic prescribing cascade with adverse events: A population-based cohort study. J Am Geriatr Soc 2024 Feb; 72:467. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38009803 https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.18683
  14. Jump up to: 14.0 14.1 Makani H, Bangalore S, Romero J, Wever-Pinzon O, Messerli FH. Effect of Renin-Angiotensin System Blockade on Calcium Channel Blocker- Associated Peripheral Edema. Am J Med. 2011 Feb;124(2):128-35 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21295192 https://www.amjmed.com/article/S0002-9343(10)00745-X/fulltext