cardiogenic shock

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Introduction

Failure to maintain adequate perfusion of vital organs secondary to impaired myocardial function.

Classification

* cancer worsens mortality at every stage[7]

Etiology

Pathology

* a mean arterial pressure of 65 mm Hg is the theshold at which there is sufficient pressure for organ perfusion (most humans)[3]

Laboratory

Complications

Management

More general terms

More specific terms

Additional terms

References

  1. Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 135-36
  2. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 211-214
  3. Jump up to: 3.0 3.1 3.2 3.3 Medical Knowledge Self Assessment Program (MKSAP) 14, 16, 17, 19. American College of Physicians, Philadelphia 2006, 2012, 2015, 2022
  4. Jump up to: 4.0 4.1 4.2 De Backer D et al Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med 2010 Mar 4; 362:779 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20200382
    Levy JH. Treating shock - Old drugs, new ideas. N Engl J Med 2010 Mar 4; 362:841. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20200389
  5. Reynolds HR, Hochman JS. Cardiogenic shock: current concepts and improving outcomes. Circulation. 2008 Feb 5;117(5):686-97 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18250279
  6. Nativi-Nicolau J, Selzman CH, Fang JC, Stehlik J. Pharmacologic therapies for acute cardiogenic shock. Curr Opin Cardiol. 2014 May;29(3):250-7 PMID: https://www.ncbi.nlm.nih.gov/pubmed/24686400
  7. Jump up to: 7.0 7.1 7.2 7.3 Jentzer JC et al. Cardiogenic shock classification to predict mortality in the cardiac intensive care unit. J Am Coll Cardiol 2019 Oct 29; 74:2117. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31548097 https://www.sciencedirect.com/science/article/pii/S0735109719362916b
    Burkhoff D et al. The SCAI cardiogenic shock staging system gets taken for a test drive. J Am Coll Cardiol 2019 Oct 29; 74:2129 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31548098 https://www.sciencedirect.com/science/article/pii/S0735109719374492
  8. Jump up to: 8.0 8.1 Mathew R, Di Santo P, Jung RG et al. Milrinone as compared with dobutamine in the treatment of cardiogenic shock. N Engl J Med 2021 Aug 5; 385:516. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34347952 https://www.nejm.org/doi/10.1056/NEJMoa2026845
  9. Jump up to: 9.0 9.1 NEJM knowledge+ Question of the Week https://knowledgeplus.nejm.org/question-of-week/5108/
    Davis AL et al. American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock. Crit Care Med 2017 Jun; 45:1061. PMID: https://www.ncbi.nlm.nih.gov/pubmed/28817482
    Yager P, Noviski N. Shock. Pediatr Rev 2010 Aug; 31:311. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20679096
    Mendelson J. Emergency department management of pediatric shock. Emerg Med Clin North Am 2018 May; 36:427. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29622332
    Bronicki RA et al. Critical heart failure and shock. Pediatr Crit Care Med 2016 Aug; 17:S124
  10. Jump up to: 10.0 10.1 10.2 10.3 Jung RG, Stotts C, Gupta A et al. Prognostic factors associated with mortality in cardiogenic shock - A systematic review and meta-analysis. NEJM Evid. 2024 Nov;3(11):EVIDoa2300323 PMID: https://www.ncbi.nlm.nih.gov/pubmed/39437131 https://evidence.nejm.org/doi/10.1056/EVIDoa2300323