diltiazem (Cardizem, Dilacor, Tiazac, Cartia, Angiotrofin, Dilcontin)

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Introduction

Tradename: Cardizem, Dilacor*.

Indications

Contraindications

pregnancy category = c

safety in lactation = ?

Dosage

Rapid atrial fibrillation:

  • Bolus 0.25 mg/kg or 20 mg IV over 2 min.
  • Rebolus 15 min later (if necessary) 0.35 mg/kg or 25 mg.
  • Infusion: 5-15 mg/hr.

Hypertension: start 30 mg PO QID, max 360 mg/day.

Tabs: 30, 60, 90, 120 mg.

Cardizem CD & Dilacor XR (sustained release)

Tabs: 120, 180, 240, 300 mg.

Cardizem SR (twice daily sustained release)

Tabs: 60, 90, 120 mg.

Cardizem LA: QD dosing; QAM or QHS[7][8]

Tabs: 120, 180, 240, 300, 360, 420 mg

Pharmacokinetics

elimination via liver

Monitor

Adverse effects

Drug interactions

Laboratory

Mechanism of action

* see Brand names for drugs in different countries

More general terms

Additional terms

Component of

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. 2.0 2.1 Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  5. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  6. Department of Veterans Affairs, VA National Formulary
  7. 7.0 7.1 Prescriber's Letter 10(4):21 2003
  8. 8.0 8.1 Prescriber's Letter 11(2):suppl 2004

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