disseminated intravascular coagulation (DIC)

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Introduction

DIC results from activation of the coagulation & fibrinolytic systems. It occurs in conditions which promote tissue factor release. DIC may be acute or chronic. Patients with chronic DIC present with bleeding such as epistaxis or gingival bleeding; the condition is problematic, but not life threatening as is acute DIC.

Etiology

Pathology

Clinical manifestations

Laboratory

Differential diagnosis

Management

More general terms

Additional terms

References

  1. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 617-618
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 17, 18. American College of Physicians, Philadelphia 1998, 2012, 2015, 2018.
  3. Schiller G, in: UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
  4. ARUP Consult: Disseminated Intravascular Coagulation - DIC The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/disseminated-intravascular-coagulation