malaria

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Introduction

From the Italian mal' aria meaning bad air.

Etiology

Epidemiology

Pathology

Genetics

Clinical manifestations

* individuals with sickle cell trait have reduced susceptibility to cerebral malaria

Laboratory

Complications

Differential diagnosis

Management

More general terms

More specific terms

Additional terms

References

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    Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022
  5. Prescriber's Letter 8(9):54 2001
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  8. 8.0 8.1 8.2 McMorran BJ et al. Platelets kill intraerythrocytic malarial parasites and mediate survival to infection. Science 2009 Feb 6; 323:797. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19197068
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  11. 11.0 11.1 11.2 11.3 11.4 The NNT: Malaria in Returning Travelers Diagnostics and Likelihood Ratios, Explained http://www.thennt.com/lr/malaria-in-returning-travelers/
    Taylor SM, Molyneux ME, Simel DL et al Does this patient have malaria? JAMA. 2010 Nov 10;304(18):2048-56 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21057136
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    White NJ et al. Spiroindolone KAE609 for falciparum and vivax malaria. N Engl J Med 2014 Jul 31; 371:403 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25075833 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1315860
    Greenwood B. Treatment of malaria - A continuing challenge. N Engl J Med 2014 Jul 31; 371:474. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25075840 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMe1407026
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  15. Baird JK Effectiveness of Antimalarial Drugs N Engl J Med 2005; 352:1565-1577. April 14, 2005. http://www.nejm.org/doi/full/10.1056/NEJMra043207
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  17. 17.0 17.1 17.2 Biddinger PD et al Case 28-2015 - A 32-Year-Old Man with Fever, Headache, and Myalgias after Traveling from Liberia. N Engl J Med 2015; 373:1060-1067. September 10, 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26352818 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMcpc1503828
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  20. 20.0 20.1 20.2 Walker M The Sweet Smell of Malaria: 'Breath Test' Promising for Dx - Mosquitoes attracted to certain odors in infected patients. MedPage Today. November 07, 2017 https://www.medpagetoday.com/meetingcoverage/astmh/69106
    Schaber C, et al Breathprinting reveals malaria-associated biomarkers and mosquito attractants American Society of Tropical Medicine & Hygiene (ASTMH) 2017; Abstract 609.
  21. Hahn WO, Pottinger PS. Malaria in the Traveler: How to Manage Before Departure and Evaluate Upon Return. Med Clin North Am. 2016 Mar;100(2):289-302. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26900114 Free PMC Article
  22. 22.0 22.1 22.2 CDC News Release. March 28, 2018 CDC: Artesunate Now First-Line Treatment for Severe Malaria in the United States. https://www.cdc.gov/media/releases/2019/s0328-artesunate-first-line-treatment.html
  23. 23.0 23.1 23.2 Hamilton WL, Amato R, van der Pluijm RW et al Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study. Lancet Infectious Diseases. July 22, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31345709 Free Article https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30392-5/fulltext
    van der Pluijm RW, Imwong M, Chau NH et al Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study. Lancet Infectious Diseases. July 22, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31345710 Free Article https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30391-3/fulltext
    Menard D, Fidock DA Accelerated evolution and spread of multidrug-resistant Plasmodium falciparum takes down the latest first-line antimalarial drug in southeast Asia. Lancet Infectious Diseases. July 22, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31345711 Free Article https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30394-9/fulltext
  24. 24.0 24.1 Balikagala B, Fukuda N, Ikeda M et al Evidence of Artemisinin-Resistant Malaria in Africa. N Engl J Med 2021; 385:1163-1171 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34551228 https://www.nejm.org/doi/10.1056/NEJMoa2101746
  25. 25.0 25.1 NEJM Knowledge+
  26. National Institute of Allergy and Infectious Diseases (NIAID) Malaria https://www.niaid.nih.gov/diseases-conditions/malaria
    Guidelines for Treatment of Malaria in the United States Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/malaria/pdf/treatmenttable.pdf
    Malaria Diagnosis & Treatment in the United States Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/malaria/diagnosis_treatment/
    CDC Malaria Hotline: (770) 488-7788 Mon-Fri 8 AM-4:30 PM EST (770) 488-7100 after hours, weekends and holidays

Patient information

malaria patient information

Database