macular edema; retinal edema
Jump to navigation
Jump to search
Etiology
- diabetic retinopathy
- central retinal vein occlusion
- hemi-retinal vein occlusion
- wet (neovascular) macular degeneration
Epidemiology
- most common cause of visual impairment due to diabetic retinopathy
- may occur in proliferative or non-proliferative phase of diabetic retinopathy
Clinical manifestations
- visual impairment
- loss of clear vision centrally (central scotoma)
- often the vision is distorted
- patients will describe letters missing in the middle of a word
Differential diagnosis
- symptoms similar to macular degeneration
- manifestation of wet (neovascular) macular degeneration
Management
- argon laser therapy
- ranibizumab (Lucentis) FDA-approved
- bevacizumab noninferior to aflibercept for treatment of macular edema due to central retinal vein occlusion[3]
More general terms
More specific terms
- clinically-significant macular edema (CSME)
- cystoid macular edema (CME)
- diabetic macular edema (DME)
Additional terms
- diabetic retinopathy (DR, proliferative {PDR} & non-proliferative)
- macula retinae, macula lutea, macula, area centralis or punctum luteum
References
- ↑ Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004; 7th edition 2010
- ↑ FDA News Release: Aug. 10, 2012 FDA approves Lucentis to treat diabetic macular edema http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm315130.htm
- ↑ 3.0 3.1 Scott IU, VanVeldhuisen PC, Ip MS et al Effect of Bevacizumab vs Aflibercept on Visual Acuity Among Patients With Macular Edema Due to Central Retinal Vein Occlusion. The SCORE2 Randomized Clinical Trial. JAMA. 2017;317(20):2072-2087 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28492910 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2626260
Bressler NM Treatment of Macular Edema Due to Central Retinal Vein Occlusion. Another Score for Repackaged Bevacizumab. JAMA. 2017;317(20):2067-2069 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28492939 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2626259