hemoglobinuria

Introduction

Hemoglobin in the urine.

Etiology

• intravascular hemolysis due to
  • hemolytic transfusion reaction (mismatched blood)
  • mechanical heart valve
• paroxysmal nocturnal hemoglobinuria (PNH)
• cold hemoglobinuria
• malarial hemoglobinuria
• march hemoglobinuria

Laboratory

• urine color: pink to red
• hemoglobin in urine

Differential diagnosis

• hematuria
  • erythrocytes will sediment if centrifuged
• myoglobinuria
  • serum creatine kinase elevated

More general terms

• sign/symptom

More specific terms

• blackwater fever (malarial hemoglobinuria)
• march hemoglobinuria; runner's anemia; exercise-induced hemolysis
• paroxysmal cold hemoglobinuria (PCH)
• paroxysmal nocturnal hemoglobinuria (PNH, Marchiafava-Micheli syndrome)
• pigment nephropathy

Additional terms

• hematuria