artemether
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Indications
- oral therapy for uncomplicated malaria
- in combination with mefloquine 25 mg/kg
- 10-12 mg/kg given in divided doses over 3-5 days
- 4 mg/kg for 3 days
- 4 mg/kg, followed by 1.5 mg/kg for 5 days
- 10-12 mg/kg given in divided doses over 3-5 days
- used alone
- 10-12 mg/kg given in divided doses over 7 days
- 4 mg/kg, followed by
- 2 mg/kg on days 2 & 3 & 1 mg/kf on days 4-7
- 10-12 mg/kg given in divided doses over 7 days
- in combination with mefloquine 25 mg/kg
- parenteral therapy for severe disease
- 3.2 mg/kg IM followed by 1.6 mg/kg/day
Adverse effects
- neurotoxicity reported in animals
More general terms
Additional terms
Component of
References
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 1186-87