tafenoquine (Arakoda, Krintafel)
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Indications
- treatment of malaria
Contraindications
Dosage
- 200 mg QD for 3 days before trip
- 200 mg per week during trip
- one 200-mg dose in week after return[5]
Tabs: 200 mg (Arakoda), 150 mg (Krintafel)
* 300 mg single-dose (Krintafel) therapy for Plasmodium vivax malaria[4][5]
More general terms
References
- ↑ RxNorm
- ↑ PubChem: 115358
- ↑ PubChem: 163761
- ↑ 4.0 4.1 Lacerda MVG, Llanos-Cuentas A, Krudsood S et al Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria. N Engl J Med 2019; 380:215-228. Jan 17. PMID: https://www.ncbi.nlm.nih.gov/pubmed/30650322 https://www.nejm.org/doi/full/10.1056/NEJMoa1710775?query=TOC
Llanos-Cuentas A, Lacerda MVG, Hien TT et al Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria. N Engl J Med 2019; 380:229-241, Jan 17. PMID: https://www.ncbi.nlm.nih.gov/pubmed/30650326 https://www.nejm.org/doi/full/10.1056/NEJMoa1802537 - ↑ 5.0 5.1 5.2 Haston JC, Hwang J, Tan KR. Guidance for Using Tafenoquine for Prevention and Antirelapse Therapy for Malaria - United States, 2019. MMWR Morb Mortal Wkly Rep 2019;68:1062-1068 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31751320 Free Article https://www.cdc.gov/mmwr/volumes/68/wr/mm6846a4.htm