tetracycline (Achromycin, Sumycin, Bristacycline)

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Introduction

Tradenames: Achromycin, Sumycin.

Indications

Contraindications

pregnancy category = d

safety in lactation = -

Dosage

Tabs: 250 & 500 mg.

Suspension: 125 mg/5 mL.

Ophthalmic: 1-2 drops BID-QID PRN or ointment every 2-12 hours

Ointment: 1% (3.72 g).

Suspension: 1% (1 mL).

Dosage adjustment in renal failure

Table

creatinine clearance dosage
50-80 mL/min 8-12 hour dosing
10-50 mL/min 12-24 hour dosing
< 10 mL/min 24 hour dosing

Pharmacokinetics

elimination via liver

elimination via kidney

Adverse effects

Drug interactions

Laboratory

Mechanism of action

More general terms

More specific terms

Additional terms

Component of

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Harrison's Principles of Internal Medicine, 13th ed. Companion Handbook. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1995, pg 164
  3. Sanford Guide to antimicrobial therapy 1997
  4. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  5. Prescriber's Letter 6(10):58, Oct, 1999
  6. 6.0 6.1 Kaiser Permanente Northern California Regional Drug Formulary, 1998
  7. 7.0 7.1 Deprecated Reference
  8. 8.0 8.1 Muanda FT, Sheehy O, Berard A Use of antibiotics during pregnancy and risk of spontaneous abortion. CMAJ 2017 May 1;189:E625-33 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28461374 <Internet> http://www.cmaj.ca/content/189/17/E625.full.pdf+html

Database