rickettsial spotted fever; tick typhus
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Classification
- Rocky Mountain spotted fever
- boutonneuse fever (Mediterranean tick typhus)
- Queensland tick typhus
- Siberian tick typhus
- African tick typhus
- Indian tick typhus
Epidemiology
- worldwide
Clinical manifestations
- fever, headache, malaise, pharyngitis[2]
- maculopapular, vesicular or petechial rash occurs early
- anterior uveitis
- dry cough[3]
Laboratory
- basic metabolic panel: hyponatremia
- Rickettsia spotted fever group antibody in serum
- Rickettsia spotted fever group DNA
- Rickettsia spotted fever group RNA
- exclusion testing
Diagnostic procedures
- skin biopsy of rash
Management
- doxycycline for 7-10 days[2]
- shorter course may be associated with relapse
- symptoms typically diminish markedly within 24 hours of appropriate therapy[3]
- prednisolone ophthalmic for uveitis
More general terms
More specific terms
- African Tick-Bite Fever; African tick typhus
- boutonneuse fever; Mediterranean spotted fever
- Indian tick typhus
- North Queensland tick typhus
- Rocky Mountain spotted fever (RMSF)
- Siberian tick typhus; North Asian Tick Fever
References
- ↑ Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 91
- ↑ 2.0 2.1 2.2 Medical Knowledge Self Assessment Program (MKSAP) 15, 19. American College of Physicians, Philadelphia 2009, 2021
- ↑ 3.0 3.1 3.2 3.3 Paras ML, Hyle EP, Foreman RK, Coffey KC Case 14-2018: A 68-Year-Old Woman with a Rash, Hyponatremia, and Uveitis. N Engl J Med 2018; 378:1825-1833. May 10, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29742372 https://www.nejm.org/doi/full/10.1056/NEJMcpc1800337