sucralfate (Carafate)

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Introduction

Tradename: Carafate.

Indications

Contraindications

pregnancy-category B

safety in lactation ?

Dosage

  • 1 g PO 1 hour before meals & QHS[1]
  • 1 gm QID or 2 g BID[2]
  • give sucralfate 1 hour before or 3-4 hours after other medicines

Tabs: 1 g.

Suspension: 1g /10 mL (420 mL).

Pharmacokinetics

Adverse effects

Drug interactions

Mechanism of action

  • forms an adherent complex that protects ulcer site from acidic environment
  • inhibits pepsin activity
  • contains aluminum

More general terms

Component of

References

  1. Jump up to: 1.0 1.1 The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Jump up to: 2.0 2.1 Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Jump up to: 4.0 4.1 Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013

Database