artemisinin
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Indications
- treatment of Plasmodium falciparum & Plasmodium vivax malaria
- may be useful for treating polycystic ovarian syndrome[4]
* use as monotherapy discouraged as resistance is spreading[2] throughout Southeast Asia
* artemisinin-resistant malaria found in Africa[3]
Mechanism of action
More general terms
More specific terms
References
- ↑ Wikipedia: http://en.wikipedia.org/wiki/Artemisinin
- ↑ 2.0 2.1 Ashley EA et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 2014 Jul 31; 371:411 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25075834 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1314981
- ↑ 3.0 3.1 Balikagala B, Fukuda N, Ikeda M et al Evidence of Artemisinin-Resistant Malaria in Africa. N Engl J Med 2021; 385:1163-1171 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34551228 https://www.nejm.org/doi/10.1056/NEJMoa2101746
- ↑ 4.0 4.1 4.2 Liu Y, Jiang JJ, Du SY et al Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction. Science. 2024 Jun 14;384(6701):eadk5382 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38870290 https://www.science.org/doi/10.1126/science.adk5382
Database
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=68827
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=452191
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2240
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9838675
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5458876
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=641602
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=49796325
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=23757058