adrenal insufficiency

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Etiology

* also see Addison's disease

Clinical manifestations

Laboratory

Radiology

* laboratory confirmed adrenal insufficiency

Complications

Management

* dexamethasone does not interfere with serum cortisol measurement[1]

see Addison's disease (primary adrenal failure) for chronic adrenal insufficiency

More general terms

More specific terms

Additional terms

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 17, 18, 19. American College of Physicians, Philadelphia 1998, 2012, 2015, 2018, 2022
    Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022
  2. 2.0 2.1 Brender E, Lynm C, Glass RM. Adrenal Insufficiency JAMA 294:2528, 2005 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16287965
  3. Annane D et al, Diagnosis of adrenal insufficiency in severe sepsis and septic shock. Am J Respir Crit Care Med 2006, 174:1319 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16973979
    Meyer NJ and Hall JB Relative adrenal insufficiency in the ICU: Can we at least make the diagnosis? Am J Respir Crit Care Med 2006, 174:1282 PMID: https://www.ncbi.nlm.nih.gov/pubmed/17158285
  4. 4.0 4.1 Marik PE et al, Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008 Jun; 36:1937 PMID: https://www.ncbi.nlm.nih.gov/pubmed/18496365
  5. 5.0 5.1 ARUP Consult: Adrenal Insufficiency The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/adrenal-insufficiency
    ARUP Consult: Adrenal Insufficiency Testing Algorithm https://arupconsult.com/algorithm/adrenal-insufficiency-testing-algorithm
  6. 6.0 6.1 Arafah BM. Hypothalamic pituitary adrenal function during critical illness: limitations of current assessment methods. J Clin Endocrinol Metab. 2006 Oct;91(10):3725-45 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16882746
  7. 7.0 7.1 Bornstein SR. Predisposing factors for adrenal insufficiency. N Engl J Med. 2009 May 28;360(22):2328-39 PMID: https://www.ncbi.nlm.nih.gov/pubmed/19474430
  8. Geriatric Review Syllabus, 8th edition (GRS8) Durso SC and Sullivan GN (eds) American Geriatrics Society, 2013
  9. Bakalov VK, Vanderhoof VH, Bondy CA, Nelson LM. Adrenal antibodies detect asymptomatic auto-immune adrenal insufficiency in young women with spontaneous premature ovarian failure. Hum Reprod. 2002 Aug;17(8):2096-100. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12151443 Free Article
  10. Bancos I, Hahner S, Tomlinson J, Arlt W. Diagnosis and management of adrenal insufficiency. Lancet Diabetes Endocrinol. 2015 Mar;3(3):216-26. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25098712
  11. Pazderska A, Pearce SH. Adrenal insufficiency - recognition and management. Clin Med (Lond). 2017 Jun;17(3):258-262. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/28572228 Free PMC Article
  12. 12.0 12.1 NEJM Knowledge+ Endocrinology

Patient information

adrenal insufficiency patient information