drugs associated with weight gain

Etiology

• phenothiazines (descending order of association)
  • chlorpromazine
  • thioridazine
  • trifluoperazine
  • mesoridazine
  • promazine
  • mepazine
  • perphenazine
  • prochlorperazine
  • haloperidol
  • loxapine
• atypical antipsychotics
  • clozapine (Clozaril)
  • olanzapine (Zyprexa)
  • quetiapine (Seroquel)
  • aripiprazole (Abilify)
  • risperidone (Risperdal)
  • ziprasidone (Geodon)
• antidepressants (descending order of association)
  • amitriptyline
  • imipramine, doxepin, phenelzine
  • amoxapine, desipramine, trazodone, tranylcypromine (by group)
  • Monoamine Oxidase Inhibitors
    • Isocarboxazid (Marplan) (controversial)
    • Phenelzine (Nardil) {most likely in this group}
    • Tranylcypromine (Parnate) (controversial)
  • Atypical antidepressants
    • Mirtazapine (Remeron)
  • Selective Serotonin-Reuptake Inhibitors
    • Citalopram (Celexa)
      • escitalopram
    • Fluoxetine (Prozac)
    • Paroxetine (Paxil)
  • Tricyclic Antidepressants
    • Amitriptyline (Elavil)
    • Clomipramine (Anafranil)
    • Desipramine (Norpramin) {least likely in this group}
    • Doxepin (Sinequan)
    • Imipramine (Tofranil)
    • Maprotiline (Ludiomil)
• mood stabilizer
  • pharmceutical lithium
• anti-epileptics (anticonvulsants)
  • valproate
  • carbamazepine (Tegretol)
  • gabapentin (Neurontin)
  • pregabalin (Lyrica)
• steroids
  • glucocorticoids
    • prednisone
  • megestrol
  • Medroxyprogesterone injection (Depo-Provera)
    • Hormones-Oral contraceptives & menopausal hormone therapy do not cause weight gain)
• antihypertensives
  • Alpha-Blockers
    • Prazosin (Minipress)
    • Terazosin (Hytrin)
  • Beta-blockers
    • Atenolol (Tenormin)
    • Propranolol (Inderal)
    • Metoprolol (Loressor, Tropol XL)
  • Centrally Acting Agents
    • Clonidine (Catapres)
    • Guanabenz (Wytensin)
    • Guanethidine (Ismelin)
    • Methyldopa (Aldomet)
  • Vasodilator
    • Minoxidil (Loniten)
• Antihistamines (H1-Blockers)
• Diphenhydramine (Benadryl)
• Fexofenadine (Allegra)
• Hydroxyzine (Vistaril)
• cyproheptadine (Periactin)
• Hypoglycemics
  • Insulin
  • Meglitinides
  • Nateglinide (Starlix)
  • Repaglinide (Prandin)
  • Sulfonylureas
    • Chlorpropamide (Diabinese)
    • Glimepiride (Amaryl)
    • Glipizide (Glucotrol)
    • Glyburide (Glynase) {appears to cause most weight gain}
    • Tolbutamide (Orinase)
  • Thiazolidinediones
    • Pioglitazone (Actos)
    • Rosiglitazone (Avandia)

More general terms

• drug adverse effect(s)

Additional terms

• weight gain