fexofenadine (Allegra)

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Introduction

Tradename: Allegra. (fexofenadine HCl) Empirical formula: C32H39NO4*HCl.

Indications

Dosage

60 mg PO BID

Tabs: 60 mg.

Dosage adjustment in renal failure

Pharmacokinetics

1/2life = 14 hours

elimination via liver

elimination via kidney

elimination by hemodialysis = -

Adverse effects

(uncommon)

Drug interactions

  • erythromycin & ketoconazole increase fexofenadine levels, but (up to 80%) but not associated with increased incidence of adverse effects

Laboratory

More general terms

Component of

References

  1. Hoest Marion Roussel
  2. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 34
  3. 3.0 3.1 Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Prescriber's Letter 8(6):33 2001
  5. 5.0 5.1 Prescriber's Letter 15(7): 2008 Comparison of Antihistamines Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=240707&pb=PRL (subscription needed) http://www.prescribersletter.com
  6. 6.0 6.1 6.2 Prescriber's Letter 18(6): 2011 OATP Fruit Juice Drug Interactions Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=270602&pb=PRL (subscription needed) http://www.prescribersletter.com

Database